報文・原著論文・総説等

​

• 2020

Nakagawa, Y.; Yamaji, F.; Miyanishi, W.; Ojika, M.; Igarashi, Y.; Ito, Y. Binding evaluation of pradimicins for oligomannose motifs from fungal mannans, Bull. Chem. Soc. Jpn. (2021), 94, 732-754.

​

• 2021

Imano, S.; Fushimi, M.; Camagna, M.; Tsuyama-Koike, A.; Mori, H.; Ashida, A.; Tanaka, A.; Sato, I.; Chiba, S.; Kawakita, K.; Ojika, M.; Takemoto, D. AP2/ERF transcription factor NbERF-IX-33 is involved in the regulation of phytoalexin production for the resistance of Nicotiana benthamiana to Phytophthora infestans, Front. Plant Sci., (2021), 12, 821574.

 

Ito, S.; Tanaka, H.; Ojika, M.; Wakamatsu, K.; Sugumaran, M. Oxidative Transformations of 3,4-Dihydroxyphenylacetaldehyde Generate Potential Reactive Intermediates as Causative Agents for Its Neurotoxicity, Int. J. Mol. Sci. (2021), 22, 11751.

 

Tanaka, H.; Ito, S.; Ojika, M.; Nishimaki-Mogami, T.; Kondo, K.; Wakamatsu, K. The Oxidation of Equol by Tyrosinase Produces a Unique Di-ortho-Quinone: Possible Implications for Melanocyte Toxicity, Int. J. Mol. Sci. (2021), 22, 9145.

 

Ariyoshi, S.; Imazu, Y.; Ohguri, R.; Katsuta, R.; Yajima, A.; Shibata, T.; Ojika, M. Identification of biosynthetic intermediates for the mating hormone a2 of the plant pathogen Phytophthora, Biosci. Biotechnol. Biochem. (2021), 85, 1802-1808.

 

Nakagawa, Y.; Kakihara, S.; Tsuzuki, K.; Ojika, M.; Igarashi, Y.; Ito, Y. A pradimicin-based staining dye for glycoprotein detection, J. Nat. Prod. (2021), 84, 2496-2501.

 

Miyanishi, W.; Ojika, M.; Akase, D.; Aida, M.; Igarashi, Y.; Ito, Y.; Nakagawa, Y. D-Mannose binding, aggregation property, and antifungal activity of amide derivatives of pradimicin A, Bioorg. Med. Chem. (2022), 55, 116590.

 

Nakagawa, Y.; Ito, Y. Mannose-binding analysis and biological application of pradimicins, Proc. Jpn. Acad., Ser. B (2022), 98, 15-29.

 

• 2022

Liu, Y.; Ojika, M. Genomic analysis of the rare slightly halophilic myxobacterium “” SMH-27-4, the producer of the antibiotic miuraenamide A, (2023), , 371.

 

Kuroyanagi, T.; Bulasag, A. S.; Fukushima, K.; Ashida, A.; Suzuki, T.; Tanaka, A.; Camagna, M.; Sato, I.; Chiba, S.; Ojika, M.; Takemoto, D. identifies host plants via the recognition of antifungal capsidiol to induce expression of a specific detoxification gene, (2022), , 1-12.

 

Sasayama, Y.; Mamiya, T.; Qi, J.; Shibata, T.; Uchida, K.; Nabeshima, T.; Ojika, M. Neuritogenic steroid glycosides from crown-of-thorns starfish: possible involvement of p38 mitogen-activated protein kinase and attenuation of cognitive impairment in senescence-accelerated mice (SAMP8) by peripheral administration, (2023), , 117144.

 

Kato, F.; Ando, Y.; Tanaka, A.; Suzuki, T.; Takemoto, D.; Ojika, M. Synthesis of aglycones, structure–activity relationships, and mode of action of lycosides as inhibitors of the asexual reproduction of , (2023), , 208-216.

 

Kato, F.; Ando, Y.; Tanaka, A.; Suzuki, T.; Takemoto, D.; Ojika, M. Inhibitors of asexual reproduction of the plant pathogen from tomato juice: structure–activity relationships and transcriptome analysis, (2022), 70, 12878-12884.

 

Kato, H.; Nemoto, K.; Shimizu, M.; Abe, A.; Asai, S.; Ishihama, N.; Matsuoka, S.; Daimon, T.; Ojika, M.; Kawakita, K.; Onai, K.; Shirasu, K.; Yoshida, M.; Ishiura, M.; Takemoto, D.; Takano, Y.; Terauchi, R. Recognition of pathogen-derived sphingolipids in , (2022), , 857-860.

 

Nakagawa, Y.; Oya, Y.; Ojika, M.; Igarashi, Y.; Ito, Y. Chemical modification of pradimicin A to suppress aggregation without impairing D-mannose-binding and antifungal activities, Tetrahedron (2022), 121, 132919.

​

• 2023

Nakagawa, Y. Recent progress in the development and application of lectin mimics, Trends Glycosci. Glycotechnol. (2023), 35, E6-E10; 中川　優、レクチンミミックの開発と応用研究の最前線、Trends Glycosci. Glycotechnol. (2023), 35, J6-J10.

 

Nakagami, S.; Notaguchi, M.; Kondo, T.; Okamoto, S.; Ida, T.; Sato, Y.; Higashiyama, T.; Tsai Y-L. A.; Ishida, T.; Sawa, S. Root-knot nematode modulates plant CLE3-CLV1 signaling as a long-distance singal for successful infection. (2023), 9, eadf4803

 

• 2024

Nakagawa, Y., Fujii, M., Ito, M., Ojika, M., Akase, D., Aida, M., Kinoshita, T., Sakurai, Y., Yasuda, J., Igarashi, Y., Ito, Y., Molecular Basis of N-Glycan Recognition by Pradimicin A and Its Potential as a SARS-CoV-2 Entry Inhibitor. Bioorg. Med. Chem. (2024) 105, 117732.

 

• 2025

Nakagawa, Y., Manabe, Y., Kondo, W., Kondo, T., Irie, K., 3,4-Dihydroquinolizinium Ring, the Core Structure of Quinocidin, as a Cysteine-Selective Electrophile. ChemPlusChem (2025) 90, e202500149.

 

Nakagawa, Y. Pradimicin A, a mannose-binding natural product: Its molecular recognition mechanism and application, Glycoforum (2025), 28, A25.

中川　優，マンノースを認識する天然物・プラディミシンA：その分子認識機構と応用，Glycoforum (2025), 28, A25.

 

Kondo, T., Irie, K., Nakagawa, Y., Structural optimization of 3,4-dihydroquinolizinium ring toward practical application for chemo-selective modification of cysteine. Tetrahedron Chem (2026), 17, 100155.

 

Nakagawa, Y. (2026) Carbohydrate-binding mechanism and therapeutic potential of lectin mimics. In The Molecular Immunology of Complex Carbohydrates-4; Suzuki, Y. Eds.; Springer-Nature, in press.

その他の刊行物

中川　優、第3の生命鎖・糖鎖に結合する低分子化合物に関する現状と展望、ファルマシア、50(11), 1117-1122(2014).